TABLE 4.
Susceptibility of C. tropicalis to antifungal agentsa
| Drug | MIC (μg/ml)
|
MFCb (μg/ml)
|
||||
|---|---|---|---|---|---|---|
| 50%c | 90%c | Range | 50% | 90% | Range | |
| Amphotericin B | 0.25 | 0.5 | 0.125-0.5 | 0.5 | 1 | 0.25-1 |
| Flucytosine | <0.25 | 0.5 | <0.25-2 | 1 | 16 | 0.25-16 |
| Fluconazole | 2 | 24 | 0.25->128 | 128 | >128 | 4->128 |
| Itraconazole | 0.25 | 8 | 0.06->32 | >32 | >32 | 32->32 |
a
Three blood and 19 colonization isolates of C. tropicalis were studied.
b
MFC, minimal fungicidal concentration.
c
Percentage of tested isolates inhibited or killed by the stated concentration.