FIG. 3.
Mobility shift assay of the complete 3′UTR (−) and shorter RNA probes of DEN4. (A) Labeled RNA consisting of nt 101 to 1 was incubated without (lane 1) or with 3 μg of S10 extract from infected U937 cells (lanes 2 to 5), in the absence (lane 2) or in the presence of a 25-fold molar excess of unlabeled 3′UTR (−) RNA (lane 3) or a 25-fold molar excess of the 3′UTR of the DEN4 genome (lane 4) or a 25-fold excess of the complete 5′UTR of the DEN4 genome (lane 5). (B) Labeled RNAs consisting of nt 101 to 1 (lane 1), nt 101 to 45 (lane 2), and nt 44 to 1 (lane 3) were incubated with 3 μg of S10 extract from infected U937 cells. Arrows indicate the migration of the complexes.