FIG. 1.

B19 virus infection induces both G₁ and G₂ arrests. (A) UT7/Epo-S1 cells were infected with 20-fold-diluted B19 virus or mock infected, and at 24 h postinfection they were left treated or treated with a mitotic inhibitor, paclitaxel, for 24 h. Subsequently, they were stained with PI for detection of DNA content and then loaded onto a fluorescence-activated cell sorting (FACS) caliber apparatus. (B) UT7/Epo-S1 cells were infected with various doses of B19 virus or mock infected and then treated with paclitaxel and PI in a manner similar to that for panel A. The percentages of G₀/G₁- and G₂/M-phase cells were calculated.