Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic displaying the DNA sequence of the first 28 amino acids of HPV16 E5WT ORF (A) and the corresponding 28-amino-acid E5XCM− mutant (B). To construct the E5XCM− HPV16 mutant, a single nucleotide, adenine, was deleted in codon 10 of the E5 ORF, disrupting the XcmI restriction site (underlined) and leading to a frameshift with a stop codon (TAA) encountered at codon 28. Only the first 10 amino acids of E5XCM− are derived from the E5 ORF.
