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. 2000 Sep;11(9):3109–3121. doi: 10.1091/mbc.11.9.3109

Figure 1.

Figure 1

Construction of CD31-EGFP fusion proteins. A schematic representation of the seven naturally expressed murine PECAM-1 cytoplasmic splice variants and the two artificial murine PECAM-1 constructs fused at the C-termini with the enhanced green fluorescent protein (EGFP). “EC”, “TM”, and “CD” indicate the PECAM-1 extracellular, transmembrane, and cytoplasmic domains respectively. FL, the full length PECAM-1 isoform; Δ, the exon(s), which is(are) spliced out from the PECAM-1 cytoplasmic domains. ΔIg2,14, a PECAM-1 construct that lacks the extracellular Ig-homology 2 region and exon 14. LS, a PECAM-1 chimeric molecule in which the PECAM-1 transmembrane and cytoplasmic domains are replaced by the analogous cell surface glycoprotein L-Selectin domains.