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. 2003 Mar 1;31(5):1464–1469. doi: 10.1093/nar/gkg245

Figure 4.

Figure 4

Comparison of the conformations of MEN 10755 in this complex with that of doxorubicin in the complex with d(CGATCG)2 (6). (A) Doxorubicin (dashed lines) and MEN 10755 intercalated at the C1pG2 step (filled lines). (B) Doxorubicin (dashed lines) and MEN 10755 intercalated at the C5pG6 step (filled lines). (C) MEN 10755 intercalated at the C1pG2 step (dashed lines) and at the C5pG6 step (filled lines). The drug molecules are superimposed by least square fitting of the common atoms on the chromophore.