Table 1.
Comparison of N2 and ric-19(pk690) animals in various assays reveals no striking differences
| Assay | N2 | ric-19(pk690) |
|---|---|---|
| Life span (n ≥ 64) | 17.3 ± 0.4 | 17.6 ± 0.4 |
| Brood size (n = 14) | 301 ± 52 | 296 ± 45 |
| Defecation interval (n = 12) | 45 ± 5 | 44 ± 4 |
| EMC frequency (n = 8) | 100% | 100% |
| Thrashing rate (n = 12) | 121 ± 8 | 117 ± 8 |
| Isobutanol C.I. | 0.96 | 0.95 |
| Isoamyl alcohol C.I. | 0.99 | 0.98 |
| Isopropanol C.I. | −0.45 | −0.57 |
| Avoidance of 4 M NaCl ring | 100% | 100% |
| T50 at 37°C (n = 12/time point) | ∼6 hours | ∼6 hours |
Life span is expressed in days. Brood size is the total number of progeny per worm. Defecation interval is the number of seconds between defecations. EMC frequency is the frequency with which an expulsion muscle contraction was observed over 12 consecutive defecation cycles per worm studied. Thrashing rate is the number of trashing motions per minute. C.I. stands for Chemotaxis Index. Osmotic avoidance is given as the percentage of worms that did not cross a 4 M NaCl osmotic barrier. T50 at 37°C is the number of hours at which 50% of the test population exposed to 37°C was deemed dead. See MATERIALS AND METHODS for details and references regarding each assay.