Schematic of pathways and inhibitors effecting EAAT2-Prom activity. EGF-R, EGF receptor; TNFR, TNF-α receptor; TRADD, TNF receptor-1-associated death domain protein; TRAF2, TNF receptor-associated factor 2; NIK, NF-κB-induced kinase; IκK, I-κB kinase; IκB, inhibitor of NF-κB; ERK, extracellular signal-regulated kinase.