Figure 10.

RACK1 regulates directional cell migration via Src. (A) Data from random Transwell migration experiments. (B) Data from haptotactic Transwell migration experiments. (C) Data from chemotactic Transwell migration experiments. To determine the relative migration, the number of positively transfected cells that migrated for each condition was normalized to the transfection efficiency and then determined as a percentage of the control cells that migrated (set to a default of 100). Data represent the average from at least three separate experiments, with error bars representing the SEM. *p < 0.05 in a Student's t test (in comparison with control).