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. 2006 Jun 8;25(12):2814–2827. doi: 10.1038/sj.emboj.7601168

Figure 8.

Figure 8

Speculative model for disordered metaphase plate. Schematics show the relationship between ordered congression and kinetochore orientation and stretching. We speculate that in EB1- or APC-depleted cells, the disruption of +end MT dynamics associated with kinetochore oscillations, perturb the orientation and stretching of centromeres.