Figure 1.

Generic models for the roles of signalling proteins at the Golgi complex. (A, B). Direct activation of Golgi signalling by endogenous events (e.g. incoming traffic)—self-regulation of the trafficking pathway (A) and/or regulation of other cellular functions (B); (C) activation of PM signals—signal translation—activation of Golgi signaling—regulation of trafficking; (D) activation of PM signals—signal translation—activation of Golgi signaling—regulation of other cellular functions (e.g. cell proliferation, motility); (E) passive residence of signalling molecules in transit to the PM.