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. 2006 Jul 4;34(11):3317–3325. doi: 10.1093/nar/gkl412

Table 2.

Definition of the AIRs for the three repressor/operator systems

Protein DNA Reference
Cro – O1R
    Active K27a,Q29a,S30a,L33a,b T3c,A4a,c,C5a,A6a,G30cT31a,b,c,T32a,b,c,T33a,G34a,T35a (50–53)
    Passive R10,K40,R41,P42
Lac – O1
    Active T5a,b,S16a,Y17b,Q18b,R22b,V30b T4c,G5a,c,T6a,G7a,A8a,C14c, T15a,c,C16a,A17a,C18a (54–57)
    Passive H29,S31
Arc – operon
    Active F10a,R13a,S32a T1c,A2c,T3c,G5c,T6a,A7a,G8a,A9a,A14c,C15c,T16c,C17a,T18a,A19a (58)
    passive Q9,N11,R16,D20,R23

The Arc monomer is composed of two symmetric subunits and only the restraints for one subunit are shown.

aConserved residues derived from the database of homology-derived secondary structure of proteins (HSSP).

bMutagenesis data.

cEthylation interference.