TABLE 2.
Apoptosis of myeloid progenitor subpopulations from SCN patients and healthy controls as determined by flow cytometry after 24 hours in culture
| Subjects | CD34+ Cells (%) | CD33+ Cells (%) | CD15+ Cells (%) |
|---|---|---|---|
| Controls (n=11) | 22 ± 5 | 10 ± 4 | 15 ± 5 |
| Patient 1 | 48 | 63 | 50 |
| Patient 2 | 53 | 78 | 73 |
| Patient 3 | 50 | 76 | 57 |
| Patient 4 (on G-CSF) | 46 | 37 | 38 |
| Patient 5 | 61 | 79 | 72 |
| Patient 7 | 55 | 80 | 62 |
| Patient 8 | 56 | 65 | 69 |
| SCN Patients (n = 7) | 53 ± 5 | 68 ± 15 | 60 ± 13 |
| Patient 9 | 4 | 9 | 78 |
| Patient 10 | 4 | 14 | 61 |
Patients 9 and 10 had SCN/AML.