Table 2.
Histologic evaluations of renal injury
| Rat treatment | Tubular necorsis | Tubular dilation | Protein casts | Medullary congestion | Glomerular damages | Interstitial stasis |
| Controls | - | - | - | - | - | - |
| Sham-operated | + * | - | - | - | - | + * |
| EDTA | - | - | - | - | - | + |
| Isc | - | + | + ** | +/++ | - | ++ |
| EDTA+Isc | - | - | - | - | - | + |
| Isc/R | + | ++ | +++ | + | - | + |
| EDTA+lsc/R | + * | ++ * | + * | - | - | + * |
| EDTA+L-NAME+Isc | - | + | + | ++ | - | ++ |
| EDTA+L-NAME+lsc/R | + | ++ | +++ | ++ | - | + |
*Focal; **Big, but focal
- = absent; + = barely present; ++ = moderate; +++ = severe
Semiquantitative analysis of renal damage representative of mean features, obtained for each group of rats.