Table 1.
Risk factor | Status | Total | CAD | CON | Odds ratio | 95% C.I | P value |
Genotype | S/S | 659 | 451 | 208 | - | - | - |
S/R | 120 | 92 | 28 | 1.52 | 0.94 – 2.45 | .07 | |
R/R | 14 | 13 | 1 | 6.0 | 0.82 – 123.6 | .05 | |
Alleles | S | 1438 | 994 | 444 | - | - | - |
R | 148 | 118 | 30 | 1.76 | 1.14 – 2.72 | .007 | |
Age | < 40 | 207 | 139 | 68 | - | - | - |
≥ 40 | 586 | 417 | 169 | 1.20 | 0.86 – 1.69 | .29 | |
Hypercholesterolemia | No | 252 | 73 | 179 | - | - | - |
Yes | 541 | 483 | 58 | 20.4 | 13.8 – 30.0 | <.001 | |
DM | No | 382 | 194 | 188 | - | - | - |
Yes | 411 | 362 | 49 | 7.16 | 4.9 – 10.2 | <.001 | |
FH | No | 544 | 376 | 168 | - | - | - |
Yes | 249 | 180 | 69 | 1.1 | 0.84 – 1.62 | .40 | |
Gender | F | 292 | 160 | 132 | - | - | - |
M | 501 | 396 | 105 | 3.11 | 2.3 – 4.3 | <.001 | |
Hypertension | No | 120 | 49 | 71 | - | - | - |
Yes | 673 | 507 | 166 | 4.42 | 2.95 – 6.62 | <.001 | |
MI | No | 599 | 368 | 231 | - | - | - |
Yes | 194 | 188 | 6 | 19.7 | 8.5 – 45.1 | <.001 | |
Obesity | No | 73 | 45 | 28 | - | - | - |
Yes | 720 | 511 | 209 | 0.65 | 0.39 – 1.08 | .07 | |
Smoking | No | 667 | 462 | 205 | - | - | - |
Yes | 126 | 94 | 32 | 1.30 | 0.84 – 2.01 | .25 | |
Hypertriglyceridemia | No | 247 | 90 | 157 | - | - | - |
Yes | 546 | 466 | 80 | 10.2 | 7.1 – 14.4 | <.001 |
DM, diabetes Mellitus; FH, family history of CAD; MI, myocardial infarction on admission; hypertriglyceridemia (>1.8 mmol/L); hypercholesterolemia (> 5.2 mmol/L) and obesity (Body Mass Index ≥ 30).