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. Author manuscript; available in PMC: 2006 Jul 13.
Published in final edited form as: J Proteome Res. 2006 Jul;5(7):1555–1567. doi: 10.1021/pr0504283

Figure 2.

Figure 2

Figure 2

The “broad” biological association networks integrated from differentially expressed proteins with relative abundance ratio (perturbed/Control) of >1.5 or <0.67. The protein complex containing Rhoa, Cdc42, Prkca, and Arf1, was highlighted inside a purple circle. A. Network resulting from caffeine treatment starting from 60 days of age. B. Network resulting from genetic variation present in DBA/2J F1 mice. Protein expression ratios are indicated by node color. Red: low-metastatic/high-metastatic > 1.5; Green: low-metastatic/high-metastatic < 0.67. The modes of interactions among the proteins were listed in the legend. Positive association and negative associations were indicated as “+” or “−” sign inside the interaction nodes.