Table 2.
Differentially expressed genes of known functions (P = 0.001) between high- and low-metastatic tumors determined using Affymetrix array.
| Probe set | Gene symbol* | Expression ratio (low-/high-metastatic groups | Description |
|---|---|---|---|
| 1450637_a_at | Aebp1 | 1.59 | AE binding protein 1 |
| 1446481_at | Apbb2 | 1.50 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| 1429012_at | Arhgef6 | 1.51 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| 1449130_at | Cd1d1 | 0.57 | CD1d1 antigen |
| 1448755_at | Col15a1 | 1.69 | procollagen, type XV |
| 1450625_at | Col5a2 | 1.77 | procollagen, type V, alpha 2 |
| 1424131_at | Col6a3 | 1.90 | procollagen, type VI, alpha 3 |
| 1421276_a_at | Dst | 1.55 | dystonin |
| 1451691_at | Ednra | 2.22 | endothelin receptor type A |
| 1438686_at | Eif4g1 | 0.56 | eukaryotic translation initiation factor 4, gamma 1 |
| 1460208_at | Fbn1 | 2.16 | fibrillin 1 |
| 1416221_at | Fstl1 | 2.15 | follistatin-like 1 |
| 1418526_at | Fusip1 | 0.66 | FUS interacting protein (serine-arginine rich) 1 |
| 1426114_at | Hnrpab | 0.61 | heterogeneous nuclear ribonucleoprotein A/B |
| 1458161_at | Kcnq1ot1 | 1.55 | KCNQ1 overlapping transcript 1 |
| 1431004_at | Loxl2 | 1.52 | lysyl oxidase-like 2 |
| 1436714_at | Lpp | 1.51 | LIM domain containing preferred translocation partner in lipoma |
| 1448655_at | Lrp1 | 1.79 | low density lipoprotein receptor-related protein 1 |
| 1446240_at | Map2k5 | 1.59 | mitogen activated protein kinase kinase 5 |
| 1434178_at | Mll3 | 1.50 | myeloid/lymphoid or mixed-lineage leukemia 3 |
| 1439364_a_at | Mmp2 | 1.89 | matrix metalloproteinase 2 |
| 1437165_a_at | Pcolce | 1.83 | procollagen C-proteinase enhancer protein |
| 1436970_a_at | Pdgfrb | 1.63 | platelet derived growth factor receptor, beta polypeptide |
| 1428896_at | Pdgfrl | 1.72 | platelet-derived growth factor receptor-like |
| 1423606_at | Postn | 1.76 | periostin, osteoblast specific factor |
| 1420747_at | Ppnr | 1.96 | per-pentamer repeat gene |
| 1444828_at | Ppp2r5c | 1.52 | protein phosphatase 2, regulatory subunit B (B56), gamma isoform |
| 1441140_at | Rere | 1.54 | RIKEN cDNA E230012J19 gene |
| 1457177_at | Rora | 1.65 | RAR-related orphan receptor alpha |
| 1426386_at | Rpl7l1 | 0.65 | ribosomal protein L7-like 1 |
| 1416589_at | Sparc | 1.71 | secreted acidic cysteine rich glycoprotein |
| 1426164_a_at | Usf1 | 0.61 | upstream transcription factor 1 |
*
Gene symbols in bold are the genes being differentially expressed between lymphatic infitration negative and positive human breast cancers.