Table 3.
Functional groups of genes with high mRNA expression ratio correlation coefficients resulting from genetic variation and caffeine exposure.
| Correlation Coefficient | P Value | Degree of freedom | Functional groups * |
|---|---|---|---|
| DBA/Control vs. Caffeine60/Control | |||
| 0.98 | 0.003 | 3 | cell cycle arrest |
| 0.92 | 0.003 | 5 | skeletal development |
| 0.90 | 0.04 | 3 | anti-apoptosis |
| 0.85 | 0.015 | 5 | negative regulation of transcription from Pol II promoters |
| 0.81 | 0.015 | 6 | protein amino acid dephosphorylation |
| DBA/Control vs. Caffeine21/Control | |||
| 0.99 | 0.0002 | 4 | negative regulation of transcription from Pol II promoters |
| 0.71 | 0.0003 | 19 | apoptosis |
| 0.78 | 0.012 | 7 | transcription |
*
Functional groups are defined by the Gene Ontology