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Consensus accessibility map for prokaryotes. The color coding on a 16S rRNA secondary-structure model of E. coli is based on rank sums for homologous target sites. Grey areas could not be covered with fully homologous probes. The different colors indicate different brightnesses (classes I through VI). Numbers in small type indicate nucleotide positions. Numbers in larger type reflect helix numbering according to Brosius et al. (3).
