Table 1.
E3-13.7 | EGF receptor | EGF receptor | |
---|---|---|---|
Infecting virusa | in724 | in724 | dl753 |
Protein half-life (h)b | 5.3 | 2.9 | 21.1 |
Turnover rate (molecules/min)c | 59 | 249 | 106 |
ERwt cells were infected with in724, which overexpresses E3-13.7, or dl753, which does not produce E3-13.7.
From linear regression analysis of metabolically labeled protein decay plots (our unpublished data). Values in the table were derived from a single experiment. Similar values were obtained for each molecule in at least two independent experiments.
Calculation made by converting arbitrary phosphorimage units to total number of molecules labeled (see MATERIALS AND METHODS).