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Gross appearance of a nude mouse normal pancreas and pancreas of mice implanted with L3.6pl human pancreas cancer cells after 5 weeks of treatment with vehicle (control) or the combination of AEE788 (oral gavage of 50 mg/kg; thrice per week) and gemcitabine (50 mg/kg, i.p.; twice per week). Arrowheads indicate pancreatic tumor. Note the extensive vascularization of pancreatic tumor in control mice.
