Table 2.
SEL1L Fold Decrease after siRNA-SEL1L-1 in Suit-2 Cells and a Summary of Differentially Expressed Genes after SEL1L Depletion
| Gene | Fold Changes* |
|---|---|
| SEL1L | 3–2.5 ± 0.25 (P < .02) |
| TIMP1 | 2.4–2 ± 0.2 (P < .03) |
| TIMP2 | 2–1.5 ± 0.25 (P < .05) |
| PTEN | 2–1.5 ± 025 (P < .05) |
| Activin A | 2–1.5 ± 025 (P < .05) |
| Activin receptor II | 2–1.5 ± 025 (P < .06) |
The values correspond to the results obtained using the two transfection reagents (± SEM).
The reported ratio indicates the observed fold decrease of gene expression in the siRNA-SEL1L-1-Suit-2 cells versus the siRNA-control-Suit-2 cells 48 hours posttransfection.