Table 7.

Subgroup Analysis of Differential TMZ and Age Effects Depending on Genetic Aberration with Respect to Survival Assessed by Cox Proportional Hazard Regression.

Alteration/Normal	Variable	Hazard Ratio CGH and LOH (95% CI)	P Value CGH and LOH (Two-Sided)
Loss 9p	TMZ	0.037 (0.0017–0.78)	.034
		0.49 (0.054–4.51)	.53
	Age (> 53 years)	0.81 (0.081–8.09)	.86
		4.31 (0.47–39.36)	.20
	TMZ x age	3.57 (0.13–99.15)	.45
	(> 53 years)	0.20 (0.015–2.71)	.23
Loss 10q	TMZ	0.85 (0.25–2.91)	.79
		5.64 (0.71–44.57)	.10
	Age (> 53 years)	10.47 (1.87–58.65)	.0076
		33.56 (3.67–307.35)	.0019
	TMZ x age	0.040 (0.0044–0.36)	.0042
	(> 53 years)	0.017 (0.0014–0.21)	.0015