Figure 1.

Chromosomal ideogram showing DNA amplifications and gene overexpression alterations in GEJ carcinomas. Chromosomes are arranged vertically next to each other. Chromosome numbers are shown on the left-hand side. DNA amplifications are shown at the right-hand side of the chromosome. The scale at the bottom indicates the frequency (%) of the change. Gene expression alterations are also shown. Overexpression changes are shown at the right-hand side of the chromosome. The length of the horizontal bar correlates with the number of altered genes in a given chromosomal location. The scale is shown at the bottom. The highest gene clusters are seen at 1q21.3, 6p21.3, and 17q21.