Figure 4.

Treatment of tumors with DBP-maf. BxPC-3 cells (a) and SU88.86 cells (b) were implanted subcutaneously onto the flank of a SCID mouse. Once the tumors had attained a volume of 100 mm³, treatment was started. Animals were given 4 ng/kg per day of DBP-maf (◯). Therapy was administered intraperitoneally. Control animals (●) received saline injections only. n=3. BxPC-3 cells were implanted subcutaneously onto the flank of a SCID mouse (c). Once the tumor had attained a volume of 100 mm³, treatment was started. Animals received intraperitoneal injections of DBP-maf at 4 ng/kg every 4 days (◯), 4 ng/kg per day (■), or 4 µg/kg per day (□). Control animals received 4 µg/kg per day of E. coli expressed human DBP (●). n=5.