Table 1.
Case no. | Age | Size | LN* | Grade | ER-α | PR | p53 | WISP-2 expression† |
1 | 65 | T2 | 3 | I | + | + | + | + |
2 | 34 | T1 | 1 | III | + | - | + | + |
3 | 39 | T2 | 2 | II | - | + | + | - |
4 | 38 | T2 | 2 | II | + | + | + | + |
5 | 67 | T3 | 2 | I | + | - | + | + |
6 | 50 | T2 | 0 | II | + | - | + | - |
7 | 37 | T2 | 10 | III | - | - | + | - |
8 | 52 | T2 | 14 | II | + | - | + | + |
9 | 84 | T3 | 0 | II | - | - | + | + |
10 | 40 | T2 | 0 | III | - | - | + | - |
11 | 64 | T2 | 0 | III | - | - | + | + |
12 | 61 | T4 | 0 | II | + | - | + | + |
13 | 35 | T1 | 0 | II | - | - | + | + |
14 | 66 | T2 | 0 | II | - | - | + | + |
15 | 58 | T3 | 4 | I | - | - | + | + |
16 | 49 | T3 | 5 | III | - | - | - | - |
17 | 75 | T1 | 0 | II | + | + | + | - |
18 | 44 | T2 | 1 | I | + | + | + | + |
19 | 40 | T2 | 0 | III | - | - | + | - |
20 | 49 | T2 | 2 | III | - | - | + | - |
21 | 50 | T2 | 0 | I | - | + | + | - |
22 | 71 | T3 | 3 | III | - | - | + | + |
23 | 50 | T3 | 25 | II | - | - | + | - |
24 | 42 | T3 | 4 | III | - | - | + | - |
25 | 64 | T1 | 5 | I | + | + | + | + |
26 | 32 | T3 | 28 | II | - | - | - | - |
27 | 60 | T2 | 0 | II | - | - | + | + |
28 | 53 | T2 | 32 | I | + | - | - | + |
29 | 73 | T2 | 0 | II | - | - | + | + |
30 | 50 | T3 | 5 | II | - | - | + | + |
31 | 46 | T3 | 4 | II | - | - | + | + |
32 | 51 | T2 | 0 | II | - | - | + | + |
33 | 59 | T1 | 0 | II | + | - | + | + |
34 | 36 | T2 | 0 | II | + | - | + | + |
35 | 53 | T3 | 31 | II | - | - | + | - |
36 | 69 | T2 | 0 | II | - | - | + | + |
37 | 34 | T2 | 6 | I | - | - | + | + |
38 | 36 | T3 | 6 | III | + | + | - | + |
39 | 60 | T3 | 6 | II | - | - | + | - |
40 | 49 | T3 | 12 | II | + | + | + | + |
41 | 48 | T3 | 0 | III | + | - | + | + |
42 | 36 | T2 | 0 | III | - | - | - | + |
43 | 34 | T1 | 0 | I | + | - | + | + |
44 | 54 | T3 | 0 | I | + | + | + | + |
45 | 41 | T1 | 0 | II | + | + | + | + |
46 | 67 | T2 | 4 | II | + | - | - | - |
47 | 43 | T1 | 0 | II | + | + | - | + |
48 | 31 | T2 | 1 | II | - | - | + | + |
49 | 41 | T3 | 0 | III | - | - | + | + |
50 | 42 | T1 | 0 | I | + | + | + | + |
51 | 55 | T2 | 5 | II | - | - | + | - |
52 | 59 | T1 | 0 | I | - | - | - | - |
53 | 52 | ‡ | 0 | II | + | + | - | + |
54 | 54 | T1 | 1 | II | + | - | - | + |
LN: axillary lymph node metastasis.
mRNA and protein expressions were determined using in situ hybridization and immunohistochemistry.
The tumor was multifocal involving many foci throughout the biopsy; therefore, tumor size cannot be evaluated.