Table II. Refinement statistics.
| dGMII | dGMII–swainsonine complex | dGMII–DMNJ complex | |
|---|---|---|---|
| Resolution (Å) | 500–2.14 | 500–1.87 | 500–1.69 |
| Rcryst (%) | 19.30 | 18.10 | 19.69 |
| Rfree (%) | 21.05 | 20.90 | 21.56 |
| Atoms (no.) | 9194 | 9202 | 9199 |
| Residues (no.) | 1014 | 1014 | 1014 |
| Water molecules (no.) | 981 | 985 | 983 |
| R.m.s.d. bonds (Å) | 0.005 | 0.005 | 0.006 |
| R.m.s.d. angles (°) | 1.32 | 1.31 | 1.33 |
| R.m.s.d. improper dihedrals (°) | 0.81 | 0.78 | 0.80 |
| Average B-factors (Å2) | 15.8 | 19.4 | 15.8 |
| Average B-factors for inhibitor atoms (Å2) | 15.6 | 12.0 | 17.4 |
| Crossvalidated σA coordinate error (Å) | 0.10 | 0.14 | 0.11 |
Rcryst = Σ||Fo| – |Fc||/Σ|Fo|, where Fo and Fc are the observed and calculated structure factors, respectively. For Rfree, the sum is extended over a subset of reflections (∼10%) excluded from all stages of refinement.