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. 2003;5(Suppl 1):S16–S21.

Table 1.

Four Possible Circumstances for Treatment with Androgen Therapy

  1. Clinical hypogonadism

    • Diseases of the HPG axis

  2. Clinical andropause

    • Clinical and biochemical age-related hypogonadism

  3. Complex age-related issues

    • Multisystem subfunction with possible androgen basis

    • Clinical picture justifying a trial of therapy if not contraindicated

  4. Targeted prevention

    • Osteoporosis - fracture prevention

    • Muscle - retention of strength

    • Mentation and mood - prevention of deterioration

HPG axis, hypothalamic-pituitary-gonadal axis