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. 2003;5(Suppl 4):S28–S33.

Table 2.

Important Points for Future Research

Physiology:
  • Modulation of prostatic androgen receptor

  • Estrogen receptor antagonists

  • Progesterone receptor antagonists

  • Anti-stromal therapy

  • Growth factor inhibition

  • Anti-angiogenesis therapy

  • Apoptosis enhancement

  • Gene therapy

Patient selection:
  • Accurate pretreatment characterization of pathology

  • Glandular/stromal ratio

  • Serum markers for glandular BPH

  • Accurate noninvasive determination of prostate size

  • Accurate noninvasive differentiation between LUTS and BOO

BPH, benign prostatic hyperplasia; LUTS, lower urinary tract symptoms; BOO, bladder outlet obstruction