Table 7.

Side Effects of Phosphodiesterase-5 Inhibitors

Drug (Dose)	Adverse Event (% Reporting)
Sildenafil*	Headache (7–25)
(25 mg, 50 mg, 100 mg)	Flushing (7–34)
	Dyspepsia (1–11)
	Nasal congestion (4–19)
	Visual effects (1–6)
Tadalafil†	Headache (11–14)
(2.5 mg, 5 mg, 10 mg, 20 mg)	Flushing (4)
N = 1561	Dyspepsia (7–10)
	Nasal congestion (4–5)
	Back pain (4–6)
	Myalgia (4–5)
Vardenafil‡	Headache (8–17)
(5 mg, 10 mg, 20 mg)	Flushing (6–13)
N = 1385	Dyspepsia (2–6)
	Nasal congestion (1–8)

^*Data from Sadovsky R et al. Int J Clin Pract. 2001;55:115–128.¹⁸

^†Data from Brock G et al. J Urol. 2002;167(suppl 4):178.⁴⁸

^‡Data from Godfishcher E et al.J Urol. 2002;167(suppl 4):178.⁴⁹