Table 3.

Kinetic parameters for activation of Met, 1 and 2 by WT and L13G MetRS

Amino acid	Synthetase	kcat, s−1	Km, μM	kcat/Km, μM−1·s−1
Met	WT*	13.3	24.3	5.47 × 10−1
AHA (1)	WT*	4.71	3328	1.42 × 10−3
Met	L13G	4.27	2109	2.02 × 10−3
ANL (2)	L13G	7.53	4831	1.56 × 10−3

*From refs. 31 and 32.