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Basal and stimulated catecholamine (NE and EP) release from chromaffin cells obtained from adrenals of control mice (Y1+/+) and Y1 knockout mice (Y1−/−). ∗∗∗, P < 0.001 compared with basal release from Y1+/+ chromaffin cells; ###, P < 0.001 compared with NE released with nicotine; †††, P < 0.001 compared with basal release from Y1−/− chromaffin cells.
