Table 3.
Cluster of E47 targets regulating genes involved in lipid metabolism
| Identified target | Function | Fold modulation |
|---|---|---|
| Cyp11a | Cytochrome P450 | 14.7 |
| Plcγ2 | Phospholipase Cγ2 | 2.8 |
| Dgke | Diacylglycerol kinase ε | 2.0 |
| Cerk | Ceramide kinase | 1.9 |
| Psap | Prosaposin | 1.6 |
| Pafah1B3 | Platelet-activating factor acetylhydrolase 1B | 1.5 |
| Gpam | Glycerol-3-phosphate acyltransferase | 1.5 |
| SC4mol | Sterol-C4-methyl oxidase-like | −1.4 |
| Cpt1β | Carnitine palmitoyltransferase 1 | −1.4 |
| Gm2a | Gm2 ganglioside activator protein | −1.8 |
| Gpld1 | Glycosylphosphatidylinositol phospholipase D1 | −11.8 |
| Sult2B1 | Sulfotransferase 2B | −41.9 |