TABLE 3.
Characteristics of 114 patients from whom M. kansasii was isolateda
| Characteristic(s) | Value for M. kansasii subtype:
|
||
|---|---|---|---|
| 1 (n = 74)b | 2 (n = 24) | 3, 4, and 7 (n = 16) | |
| Demography | |||
| Mean age ± SD (yr) | 45 ± 19.5c | 40.5 ± 16.7c | 76.0 ± 22.3 |
| Male | 46 (62.0) | 15 (62.5) | 11 (68.7) |
| Urban residents | 42 (56.7) | 15 (62.5) | 11 (68.7) |
| Swiss | 54 (73.0) | 20 (83.3) | 11 (68.7) |
| Risk factors | |||
| HIV infection | 23 (31.1)c | 15 (62.5)c | 1 (6.2) |
| Corticoid use | 5 (6.7) | 5 (20.8) | 3 (18.7) |
| Tobacco use | 43 (58.1) | 18 (75.0) | 8 (50.0) |
| COPD | 15 (20.3) | 6 (25.0) | 9 (56.2) |
| Other pulmonary diseases | 45 (60.8) | 16 (66.7) | 9 (56.2) |
| Source of isolated | |||
| Pulmonary | 67 (90.5) | 19 (79.2) | 9 (56.2) |
| Nonpulmonary | 20 (27.0) | 8 (33.3) | 4 (25.0) |
| Disseminated | 17 (23.0)c | 7 (29.2)c | 0 (0.0) |
| Clinical presentation | |||
| Asymptomatic | 4 (5.4) | 2 (8.3) | 3 (18.7) |
| Systemic symptoms | 55 (74.3)c | 18 (75.0)c | 6 (37.5) |
| Respiratory symptoms | 60 (81.1) | 20 (83.3) | 13 (81.2) |
| Median duration of symptoms (wk) | 8c | 6c | 2 |
| Results of chest radiography | |||
| Normal | 9 (12.1) | 1 (4.2) | 0 (0.0) |
| Abnormale | 64 (86.5) | 22 (91.7) | 16 (100.0) |
| Interstitial infiltrate | 40 (54.1) | 8 (33.3) | 6 (37.5) |
| Cavitation | 17 (23.0)c | 2 (8.3) | 0 (0.0) |
| Alveolar infiltrate | 7 (9.5)c | 5 (20.8) | 5 (31.3) |
| Nodular infiltrate | 4 (5.4) | 3 (12.5) | 0 (0.0) |
| Mediastinal enlargement | 4 (5.4) | 4 (16.7) | 1 (6.3) |
| Pleural effusion | 3 (4.1) | 0 (0.0) | 1 (6.3) |
| Other | 3 (4.1) | 1 (4.2) | 3 (18.8) |
| Not available | 1 (1.4) | 1 (4.2) | 0 (0.0) |
| Results of smear examination | |||
| Positive | 24 (32.4)c | 4 (16.7) | 0 (0.0) |
| Negative | 22 (29.7) | 11 (45.8) | 10 (62.5) |
| Not available | 28 (37.8) | 9 (37.5) | 6 (37.5) |
| Antimycobacterial therapy | 53 (71.6)c,f | 10 (41.7)c | 4 (35.0) |
| Outcome | |||
| Cured | 32 (43.2) | 7 (29.2) | 7 (43.7) |
| Treatment failure | 8 (15.1) | 2 (20.0) | 0 (0.0) |
| Death | 35 (47.3)c | 11 (45.8)c | 2 (12.5) |
| Attributed to M. kansasii | 17 (22.9)c | 6 (25.0) | 0 (0.0) |
a
Numbers in parentheses are percentages.
b
n, total number of patients.
c
P is <0.05 compared to values for subtypes 3, 4, and 7.
d
Patients may have M. kansasii strains isolated from multiple body sites.
e
Patients may have more than one type of radiologic lesion.
f
P is <0.05 compared to values for subtype 2.