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Sequence analysis of rpoB genes found in RifrM. tuberculosis strains in Shanghai
| Mutated codon | Mutation | Amino acid change | No. (%) of mutated sites |
|---|---|---|---|
| 531 | TCG→TTG | Ser→Leu | 21 (51.2) |
| 526 | CAC→TAC | His→Tyr | 5 (12.2) |
| CAC→GAC | His→Asp | 3 (7.3) | |
| CAC→AAC | His→Asn | 1 (2.4) | |
| 516 | GAC→GTC | Asp→Val | 1 (2.4) |
| GAC→GGCa | Asp→Gly | 3 (7.3) | |
| 511 | CTG→CCGa | Leu→Pro | 3 (7.3) |
| 513 | CAA→CTA | Gln→Leu | 1 (2.4) |
| 533 | CTG→CCG | Leu→Pro | 1 (2.4) |
| 514-515 | TTC ATG deletionb | 1 (2.4) | |
| 516-520 | GAC CAG AAC AAC CCG deletionc | 1 (2.4) |
