TABLE 3.
Methods for antifungal susceptibility testing for fluconazole and comparison of results with the NCCLS reference range
| Organism | Reference range (μg/ml) | NCCLS broth microdilution results (μg/ml) | % Agreement | Sensititre YeastOne results (μg/ml) | % Agreement | Etest results (μg/ml) | % Agreement | Overall agreement (%) |
|---|---|---|---|---|---|---|---|---|
| C. albicans ATCC 24433 | 0.25-1.0 | 0.25-4.0 | 15 | 2.0-8.0 | 0 | 1.5-6.0 | 0 | 5 |
| C. krusei ATCC 6258 | 16.0-64.0 | 4-64 | 86 | 16.0-32.0 | 100 | 32.0-64.0 | 100 | 95 |
| C. lusitaniae ATCC 200950 | 0.25-1.0 | 0.25-16.0 | 86 | 0.25-0.5 | 100 | 0.12-1.5 | 67 | 84 |
| C. parapsilosis ATCC 22019 | 2.0-8.0 | 1.0-8.0 | 86 | 2.0-4.0 | 100 | 2.0-8.0 | 100 | 95 |
| C. tropicalis ATCC 750 | 0.5-2.0 | 1.0-4.0 | 100 | 1.0-2.0 | 100 | 0.5-1.5 | 67 | 89 |
| % Overall agreement | 75 | 80 | 67 | 74 |