TABLE 1.
Insertions in the p6gag region and mutations at cleavage sites in antiretroviral-naive and pretreated HIV-infected patients
p7-p1-p6gag genotype | No. of patients
|
P value | |
---|---|---|---|
Drug naive (n = 74) | Pretreated (n = 82) | ||
Insertion at PTAP motif | 13 | 10 | 0.345 |
Insertion at KQE motif | 0 | 10 | 0.002 |
Total insertions in p6gag | 13 | 20 | 0.300 |
Point mutations | |||
A541/V in p7gag | 1 | 14 | 0.001 |
I5F/LV in p1gag | 4 | 14 | 0.023 |
P5I/L/T in p6gag | 8 | 28 | 0.001 |
E20A/G/K in p6gag | 0 | 7 | 0.01 |