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Observed and predicted survival rates of AVA-vaccinated guinea pigs challenged with diverse B. anthracis isolates. Twenty isolates were used to construct the model of virulence (A), and a set of 12 isolates was then used to validate the model (B). While there is some deviation between the predicted and observed percentages of survival of guinea pigs when an MLVA cluster factor and plasmid ratio covariates were used, the model is surprisingly robust in performance.
