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. 2002 Jan;4(1):9–18. doi: 10.1038/sj.neo.7900194

Figure 1.

Figure 1

Effect of exogenous androgen (R1881) on proliferation of AR+ (DAR17) and AR- (DZeo1) cells. Proliferation in control medium (N.med) was compared with proliferation in the presence of R1881 over a concentration range of 10-13 to 10-6 M, and also 4-hydroxyflutamide (4-OHF). None of the exogenous steroids has any effect on the proliferation of DZeo1. In contrast, there is an increasing inhibitory effect of R1881 on the growth of DAR19 first apparent at 10 nM. The decline in cell number seen in both cell lines from 150 hours onwards is a result of serum starvation.