Fig. 6. Summary of myoblast phenotypes generated by expression of different FKHR mutants. Top left panels show the differentiation of wild-type, FKHR mutants, PTEN- and DN-Akt-expressing myoblasts at 0 and 24 h of differentiation. No difference in the extent of fusion between any of these populations was observed. Lower left panels show the temporal expression of early (MyoD), intermediate (myogenin) and late (myosin heavy chain) myogenic markers during 2 days of differentiation, which was the same for all samples. Right panels show the complete range of fusion phenotypes generated by the different FKHR mutants.