Table 1.

Dynein intermediate chain sequence similarities with Drosophila Cdic19C

	Percent identity (% similarity)	Amino acid residues (range, 1–642)
Cytoplasmic
Mouse IC2	56 (65)	2–640
Rat IC2a	55 (65)	4–640
Rat IC1	51 (60)	2–640
Human IC1	51 (59)	2–640
Caenorhabditis elegans	40 (50)	3–641
Dictyostelium	43 (50)	74–639
Yeast	30 (43)	361–530
Axonemal
Chlamydomonas IC78	28 (38)	246–623
Chlamydomonas IC70	28 (38)	233–628
Sea urchin IC2	25 (35)	209–642
Sea urchin IC3	25 (36)	216–623

Amino acid sequence comparisons of the Drosophila dynein intermediate chain with both cytoplasmic and axonemal intermediate chains from other species. Sequences were aligned using the GCG program BESTFIT with the use of default parameters. Accession numbers are: Drosophila, AF263371, and Cdic2a, AF070692 (Nurminsky et al., 1998a); rat IC1, X66845 (Paschal et al., 1992); rat IC2a, U39044 (Vaughan and Vallee, 1995); mouse IC2, AF063231; human IC1, AF063228 (Crackower et al., 1999); C. elegans, cosmid CELC17H12, AF045642 (C. elegans Genome Sequencing Consortium, 1998); Dictyostelium, U25116 (Ma et al., 1999); yeast, U16820 (Geiser et al., 1997); Chlamydomonas IC78, U19120 (Wilkerson et al., 1995); Chlamydomonas IC70, X55382 (Mitchell and Kang, 1991); sea urchin IC2, D38538; sea urchin, IC3, D28863 (Ogawa et al., 1995).