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Expression of cell-surface antigens by circulating HSV-2–specific CD8+ T cells. (a) PBMCs from donor 4196 were gated for lymphocyte size and scatter, high CD8α expression, and binding of tetramer B7-RPR, which is specific for VP22 a.a. 49–57. Expression of CD28, CD62L, and CCR7 is displayed in the indicated histograms. (b) Similar data for CD8α-high lymphocytes, which did not bind tetramer B7-RPR, from the same donor.
