Table 2.
Exceptions to residue invariance
| Protein | Invariant residue* | Exceptions: organism (homologous residue) | ||
| TrpEa | 57P | Sso (A) | ||
| 60D | Hal (E) | |||
| 61G | Ctr (N) | |||
| 64I | Mth (V) | |||
| 183T | Ctr (R) | |||
| 184G | Hin (S) | |||
| 211G | Ctr (R) | |||
| 212F/L | Ctr (R) | |||
| 213G | Ctr (D) | Paero (A) | Ape (S) | |
| 234G | Ctr (K) | |||
| TrpEb_1 | 10G | Ctr (H) | Cps-2 (E) | Cps-1 (Y) |
| 21L | Cje (A) | |||
| 41F | Asp-1 (Y) | |||
| 55R | Mth-1 (K) | |||
| 78E | Ccr (D) | |||
| 79D | Rca-1 (E) | Paeru (E) | ||
| 80L | Mth-1 (M) | Dra (Q) | ||
| 82H | Mba-2 (Q) | Dra (F) | ||
| 94Q | Rca-2 (E) | |||
| 96L | Rpa-1 (M) | Spn (W) | Bsp (M) | |
| 97L | Cps-2 (I) | |||
| 102G | Bsp (K) | |||
| 114Q | Rpa-1 (M) | Paeru (M) | ||
| 124A | Zma-2 (R) | Cps-1 (G) | ||
| 133F/Y | Rca-2 (H) | |||
| 141R | Rca-2 (K) | |||
| 146V | Mba-1 (A) | |||
| 149M | Cps-2 (I) | |||
| 153G | Hal (D) | |||
| 156V | Cje (I) | |||
| 159V | Bha (A) | |||
| 162G | Cdip-2 (E) | |||
| 167K | Cdip-2 (S) | Sau (S) | ||
| 173A | Hal (T) | Rca-2 (C) | ||
| 177W | Cps-2 (F) | Rca-2 (Y) | ||
| 186Y | Cps-2 (F) | Rca-2 (F) | ||
| 208I | Xfa (V) | |||
| 213R/K | Bpe (L) | |||
| 224P | Cje (V) | |||
| 225D | Bha (T) | Rca-2 (A) | ||
| 267H | Rca-2 (N) | |||
| 269A | Sau (L) | Mba-1 (S) | ||
| 274G | Aac (A) | |||
| 299S | Rca-2 (T) | |||
| 310G | Mba-2 (S) | |||
| 345I | Rca-2 (V) | |||
| 383D | Yps (E) | |||
| Protein | Invariant residue† | Exceptions: organism (homologous residue) | ||
| TrpEb_2 | P10 | Paero-1 (gap) | ||
| Y14 | Aae-2 (L) | |||
| E54 | Sso-1 (Q) | |||
| L86 | Msm-2 (F) | |||
| E87 | Paero-2 (D) | |||
| E101 | Paero-2 (Q) | |||
| S108 | Paero-2 (N) | |||
| A114 | Mba-3 (S) | |||
| W138 | Sso-1 (R) | |||
| G176 | Fac (N) | |||
| S184 | Sso-1 (T) | |||
| S203 | Fac (T) | |||
| I206 | Msm-2 (M) | |||
| A207 | Fac (G) | |||
| S209 | Ape-1 (A) | |||
| E210 | Sso-2 (D) | |||
| G226 | Fac (A) | |||
| N265 | Paero-2 (S) | |||
| P272 | Mba-3 (E) | |||
| G300 | Cte-2 (A) | |||
| F/Y325 | Mba-3 (H) | |||
| F371 | Ape-1 (M) | |||
| P379 | Fac (A) | |||
| S410 | Ath-3 (C) | |||
*Residues are numbered according to the S. typhimurium sequence. †Residues are numbered according to the P. furiosus sequence.