Table 2.

hTERT Expression in Human Tumors.

Tissues/Tumors	Telomerase Activity		Location Cell Type with Expression	Level of Expression*
Breast
FC†	0/4	-	Epithelial component	+
Fibroadenoma	5/12	low	Epithelial component	+
DCIS‡	3/3	low	Cancer cells	+ +
LCIS§	2/2	low	Cancer cells	+ +
Invasive carcinoma	84/86	low-high	Cancer cells	+ +
Lung
SCLC	9/9	high	Cancer cells	+ +
NSCLC	23/26	low-high	Cancer cells	+ +
Stomach
Adenoma	2/3	low	Mucosal basal cells/lymphocytes	+
CIS	4/4	low	Cancer cells	+ +
Invasive carcinoma	50/52	low-high	Cancer cells	+ +
Colon
Adenoma	14/14	low-high	Basal cells of crypt/lymphocytes	+ (+ +)
CIS	3/3	low-high	Cancer cells	+/+ +
Invasive carcinoma	96/100	low-high	Cancer cells	+ +
Liver
HCC	15/16	high	Cancer cells/lymphocytes	+ +
Pancreas
Duct cell carcinoma	41/42	high	Cancer cells	+ +
Islet cell carcinoma	3/3	low-high	Cancer cells	+
Childhood
Neuroblastoma	102/108	low-high	Cancer cells	-/+ +
Wilms	12/12	high	Cancer cells	+/+ +
Hepatoblastoma	15/15	low-high	Cancer cells	+/+ +

^*Telomerase activity detected by TRAP assay was divided into three groups: high, low, and - (negative). hTERT IHC signals were divided into three groups: + + (strong), + (weak), and - (no staining).

^†Fibrocystic disease.

^‡Ductal carcinoma in situ.

^§Lobular carcinoma in situ.