Table 1.
Median (range) bronchoalveolar lavage fluid (BALF) and serum levels (pg/ml) of cytokines and adhesion molecules measured in the three groups of patients and controls
Group 1 (n = 23) | Group 2 (n = 14) | Group 3 (n = 28) | ||||
BALF | Serum | BALF | Serum | BALF | Serum | |
IL-1 | 267 (0–2030) | 364 (3–908) | 339 (0–630) | 408 (160–556) | 179 (0–860) | 178 (3–563) |
TNF-α | 463 (0–2600) | 204 (60–790) | 210** (0–680) | 383 (160–490) | 145** (0–643) | 254 (93–1280) |
SICAM-1 | 970 (540–2460) | 320 (66–1120) | 1440 (460–2220) | 365 (220–620) | 1710 (260–4620) | 255 (66–900) |
sVCAM | 350 (156–528) | 355* (66–900) | 416 (92–536) | 330* (180–510) | 330 (52–924) | 150 (66–720) |
*P < 0.05 versus group 3; **P < 0.0001 versus group 1. Comparisons were done using the Kruskal-Wallis test. IL-1 = interleukin-1; TNF-α = tumour necrosis factor-alpha; sICAM-1 = serumintercellular adhesion molecule-1; sVCAM = serum vascular adhesion molecule