Table 2.
Clinical characteristics of subgroups of COPD patients without and with radiological emphysema *
| Patients without radiological emphysema | Patients with radiological emphysema | ||
| (n = 32) | (n = 127) | P-value † | |
| Age (year) | 66 ± 8 | 66 ± 8 | 0.70 |
| Sex (male/female) | 16/16 | 86/41 | 0.062 |
| FEV1% predicted | 46 ± 15 | 35 ± 11 | 0.001 |
| Smoking behavior | |||
| -never smoked/(ex)-smoker | 4/28 | 1/126 | 0.001 |
| -pack years | 26 ± 22 | 34 ± 18 | 0.037 |
* Values are expressed as mean ± SD or as absolute numbers. † The Mann-Whitney U test was used for differences in age and FEV1 between groups. The χ2-test was used to detect significant differences in genotype frequencies and sex. Statistical significance was defined as p < 0.01 using Bonferroni correction.