TABLE 2.
MAbs to other species tested in this study
| Reference MAb | Immunogen | Specificity (kDa) | Reactivities with other speciesa | Reactivity with R. felis |
|---|---|---|---|---|
| AF1-B9 | R. africae | 155 | 5, 9, 10, 13, 16, 17, 20, 24, 27, 28 | Negative |
| AF1-D12 | R. africae | 155 | 5, 9, 10, 13, 16, 17, 20, 24, 27, 28 | Negative |
| AF4-C8 | R. africae | 155 | 2, 5, 9, 10, 13, 14, 16, 17, 18, 19, 20, 24, 27, 29 | Negative |
| AF6-D6 | R. africae | 120 | 2, 5, 7, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 24, 25, 26, 27, 28, 29, 30 | Positive |
| AF6-E10 | R. africae | 155 | 2, 5, 9, 10, 13, 14, 15, 16, 17, 18, 23, 26, 28, 29 | Negative |
| AF8-F3 | R. africae | 120 | 2, 5, 9, 10, 24, 27, 28 | Negative |
| RC1-C7 | R. conorii | 155 | 13, 16, 17, 20, | Negative |
| RC1-H10 | R. conorii | 120 | 1, 2, 3, 5, 7, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, | Negative |
| RC2-F2 | R. conorii | 120 | 1, 2, 5, 9, 10, 13, 14, 15, 16, 17, 18, 19, 20, 20, 24, 25, 26, 27, 28 | Negative |
| RC2-D9 | R. conorii | 120 | 7, 9, 10, 13, 14, 15, 16, 17, 18, 19, 20, 28, 29 | Negative |
| RC2-E3 | R. conorii | 155 | 13, 16, 17, 18, 20 | Negative |
| RC2-G12 | R. conorii | 155 | 5, 13, 16, 17, 18, 19, 20, 29 | Negative |
| RC3-G4 | R. conorii | 155 | 1, 2, 5, 9, 10, 12, 13, 14, 16, 17, 20, 24, 26, 27, 28, 30 | Negative |
| RC3-G7 | R. conorii | 120 | 1, 2, 5, 13, 14, 16, 17, 18, 19, 20, 24, 27 | Negative |
| RC4-C1 | R. conorii | 155 | 5, 13, 16, 17, 18, 19, 20, | Negative |
| RC5-A5 | R. conorii | LPS-like antigen | 1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 | Negative |
| RC7-G11 | R. conorii | 120 | 5, 13, 14, 16, 17, 18, 19, 20, | Negative |
| RC8-D1 | R. conorii | 120 | 1, 2, 5, 9, 10, 13, 14, 16, 17, 18, 19, 20, 23, 24, 27, 28, 29 | Negative |
| RC8-C9 | R. conorii | 120 | 13, 16, 17, 18, 19, 20, | Negative |
| RC9-B8 | R. conorii | 120 | 1, 2, 5, 9, 10, 13, 14, 15, 16, 17, 18, 19, 20, 24, 25, 26, 27, 28 | Negative |
| RC9-G11 | R. conorii | 120 | 13, 16, 17, 18, 19, 20 | Negative |
| RC10-A3 | R. conorii | 120 | 1, 2, 3, 5, 7, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 | Positive |
| RC10-B5 | R. conorii | 120 | 13, 16, 17, 18, 19, 20 | Negative |
| MA1-D2 | R. massiliae | Not identified | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 | Negative |
| MA4-C11 | R. massiliae | 120 | 7, 21, 22 | Negative |
| MA6-F3 | R. massiliae | 120 | 21, 22 | Negative |
| MA7-A11 | R. massiliae | 120 | 3, 5, 15, 21, 22, 25 | Negative |
| MA8-F6 | R. massiliae | 120 | 15, 21, 22 | Negative |
| AK1-C12 | R. akari | 120 | 4 | Negative |
| AK2-B41 | R. akari | 120 | 4, 6 | Positive |
| SV10-D2 | R. slovaca | 120 | 1, 2, 5, 13, 14, 16, 17, 18, 19, 20, 21, 22, 29 | Negative |
| SV10-E8 | R. slovaca | 120 | 1, 2, 9, 10, 13, 16, 17, 18, 19, 20, 24, 27, 28, 29 | Negative |
| P11A12 | R. prowazekii | 120 | 31 | Negative |
| P9H3 | R. prowazekii | 120 | 31 | Negative |
| P5G11 | R. prowazekii | 120 | 31 | Negative |
| P12A12 | R. prowazekii | 120 | 31, 33 | Negative |
| P2G9 | R. prowazekii | 120 | 31 | Negative |
| P12E11 | R. prowazekii | 120 | 31, 33 | Negative |
| P2H12 | R. prowazekii | 120 | 31 | Negative |
| P8H11 | R. prowazekii | 120 | 31, 32, 33 | Negative |
| P11C8 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P10B8 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P6F12 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P12E12 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P7F12 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P9G12 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P10F12 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P5G7 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| P12H10 | R. prowazekii | LPS-like antigen | 31, 32, 33 | Negative |
| T7A5 E10E10 | R. typhi | 120 | 32 | Negative |
| T6A10G3F3 | R. typhi | 120 | 32 | Negative |
| T4D2C9H7 | R. typhi | 120 | 32 | Negative |
| T7F5B12G8 | R. typhi | 120 | 5, 31, 32 | Negative |
| T7F5H8H9 | R. typhi | 120 | 26, 32 | Negative |
| T7F2H8E10 | R. typhi | 120 | 32 | Negative |
| T7F12F11H10 | R. typhi | 120 | 26, 32 | Negative |
| T7G10F7G12 | R. typhi | 120 | 30, 32 | Negative |
| T7G10F7E11 | R. typhi | 120 | 30, 31, 32 | Negative |
| T7G2F8G11 | R. typhi | 120 | 26, 30, 12, 15, 33, 32 | Negative |
| T7G2G9H12 | R. typhi | 120 | 26, 30, 12, 15, 32 | Negative |
| T7G11A8G12 | R. typhi | 120 | 31, 32 | Negative |
| T1F3F9E9 | R. typhi | 120 | 31, 32, 33 | Negative |
| T2G7F11A12 | R. typhi | LPS-like antigen | 31, 32, 33 | Negative |
| T6F1E10 | R. typhi | LPS-like antigen | 31, 32, 33 | Negative |
a
1, R. africae (Z9-Hu); 2, R. africae (Ethiopian), 3, R. aeschlimannii (MC16); 4, R. akari [MK(Kaplan)]; 5, Astrakhan fever rickettsia (A167); 6, R. australis (Philips); 7, strain Bar 29; 8, R. bellii (369L42-1); 9, strain BJ90; 10, “R. mongololimonae” (HA-91); 11, R. helvetica (C9P9); 12, R. honei (RB); 13, R. conorii Indian; 14, R. conorii Israeli (ISTT CDC1); 15, R. japonica (YH); 16, R. conorii Kenya; 17, R. conorii Manuel; 18, R. conorii M-1; 19, R. conorii Moroccan; 20, R. conorii Seven; 21, R. massiliae (Mtu 1); 22, R. massiliae (GS); 23, R. montanensis (tick stain); 24, R. parkeri (Maculatum 20); 25, R. rhipicephali (3-7-6); 26, R. rickettsii (Sheila Smith); 27, strain S; 28, R. sibirica (246); 29, R. slovaca (13-B); 30, Thai tick typhus rickettsia (TT-118); 31, R. prowazekii (Breinl); 32, R. typhi (Wilmington); 33, R. canadensis (2678); 34, R. felis (Marseille).