Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Metabolization of adenosine to inosine occurred rapidly in vivo mainly by the enzyme adenosine deaminase. The A3AR agonist, IB-MECA, resists degradation by adenosine deaminase, due to substitution, at the 2-position of adenosine, combined with modifications at N6 and 5′-positions [26,27].
