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. 2003 Apr;77(7):4004–4014. doi: 10.1128/JVI.77.7.4004-4014.2003

FIG. 5.

FIG. 5.

Altered receptor phenotype on CCL3−/− virus-specific CD8+ T cells. CCL3+/+ and CCL3−/− mice were infected i.c. with MHV, and the activation state of virus-specific CD8+ T cells was analyzed at 7 and 12 days p.i. Cells isolated from the CLN were stained for CD8, tetramer (S510-518), and either CD25, CD62L, or CD44. Contour blots represent CD62L, CD44, and CD25 expression on gated tetramer (S510-518)-positive, CD8+ T cells. The percentage of tetramer-positive cells expressing each receptor is shown in the upper right quadrant for each blot. The contour blots shown represent gated populations of tetramer-positive CD8+ T cells isolated from one representative mouse from each group. The experiment was performed in duplicate with three mice per group.