TABLE 3.

Inhibition of HIV-1 subtype C viruses by CCR5 and CXCR4 inhibitors

Virus	Subtype	Phenotype	% Inhibition by CCR5 inhibitora				% Inhibition by CXCR4 inhibitor AMD3100 ata:
			RANTES at:		PRO 140 at:
			19 nM	4 nM	167 nM	33 nM	500 nM	100 nM
PCP1	C	R5, CXCR6	97	68	98	88	34	18
CM1	C	R5	87	49	78	59	0	8
CM7	C	R5	94	89	97	100	3	19
SW5	C	R5	100	75	100	100	19	6
SW23	C	R5	100	89	98	94	0	0
SW26	C	R5	100	91	93	87	8	0
SW29	C	R5	98	74	98	91	13	0
SW38	C	R5	100	34	100	96	0	0
CM9	C	R5X4, CXCR6, BOB, R3	36	36	34	13	97	58
SW7	C	X4	0	24	0	5	100	87
SW12	C	X4	0	0	0	0	86	31
SW20	C	R5X4	0	0	79	0	100	0
SW30	C	R5X4	24	9	8	39	85	3
DJ258	A	R5	100	82	100	98	46	0
92RW026	A	R5	98	69	100	100	63	23
JR-FL	B	R5	99	71	100	98	0	36
92US714	B	R5	95	60	100	100	0	0
92US077	B	R5X4	17	48	48	41	99	76
CM235	E	R5	95	62	100	97	22	2
92TH001	E	R5	100	88	99	98	60	21

^aInhibition of >90% is bolded, and inhibition of <90% is in italics.